d1r selective agonist skf38393 Search Results


d1r agonist  (Tocris)
93
Tocris d1r agonist
a Dopamine concentration (in pg/μL) in infected Control (Ctrl, white) and Brainless (BR – , gray) embryos at early stage 35, measured by liquid chromatography–mass spectrometry (LC–MS/MS). Unpaired t -test * P < 0.05. b Survival rates (in percentage) of Ctrl (white) and BR – (gray) infected embryos after pharmacological treatment with drugs targeting the type-1 or type-2 family of dopamine (DA) receptors <t>(D1R,</t> D2R). Two-way ANOVA P < 0.01; P values after Bonferroni post hoc test are indicated as ** P < 0.01, ns P > 0.05. a , b Data represent the mean and S.D. of three independent replicates of 30 embryos. Each replicate is shown by one dot. See also Supplementary Fig. . c , d Drawings represent the morphological and molecular events occurs in response to infection, in presence ( c ) or absence ( d ) of brain. Unique neural- and immune-related pathways are indicated in blue. Upregulation and downregulation of transcripts are indicated in black. E. coli is represented by red circles; apoptotic cells are represented by cyan circles; mmp7 + cells (early macrophages) are represented by pink stars; dopamine-activated macrophages are represented with a D on the pink star. Complete list of genes is presented in Supplementary Data . Green = down gene, Red = up gene. All measured genes found in a pathway are located in Supplementary Data .
D1r Agonist, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/d1r+selective+agonist+skf38393/SKF+38393+hydrobromide/pmc07000827-421-13-16
Average 93 stars, based on 1 article reviews
d1r agonist - by Bioz Stars, 2026-10
93/100 stars
  Buy from Supplier
d1r agonist skf 38393 hydrochloride  (MedChemExpress)
94
MedChemExpress d1r agonist skf 38393 hydrochloride
( A ) Experimental design. ( B ) Schematic of viral transfection. ( C ) Representative images of virus injection and fiber implant in CL. ( D ) Heatmap of DA3h fluorescence (left), quantification (middle), and AUC (right) of ΔF/F in CL. n = 5 mice/group. ( E ) The protein levels of <t>D1R</t> in CL. The protein levels of D1R following the METH CPP-Test. n = 3 mice/group. ( F ) Immunofluorescence of c-Fos + CaMKII + D1R + neurons in CL. Mean gray value of D1R CaMKII following METH CPP-Test. n = 6 mice/group. * P < 0.05. Two-tailed unpaired t test ( D – F ). Scale bars: 100 μm ( C and F ).
D1r Agonist Skf 38393 Hydrochloride, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/d1r+selective+agonist+skf38393/SKF+38393+hydrochloride/pmc12948420-268-6-11
Average 94 stars, based on 1 article reviews
d1r agonist skf 38393 hydrochloride - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier
d1r agonist skf38393 3 m  (HFS LTD)
90
HFS LTD d1r agonist skf38393 3 m
( A ) Experimental design. ( B ) Schematic of viral transfection. ( C ) Representative images of virus injection and fiber implant in CL. ( D ) Heatmap of DA3h fluorescence (left), quantification (middle), and AUC (right) of ΔF/F in CL. n = 5 mice/group. ( E ) The protein levels of <t>D1R</t> in CL. The protein levels of D1R following the METH CPP-Test. n = 3 mice/group. ( F ) Immunofluorescence of c-Fos + CaMKII + D1R + neurons in CL. Mean gray value of D1R CaMKII following METH CPP-Test. n = 6 mice/group. * P < 0.05. Two-tailed unpaired t test ( D – F ). Scale bars: 100 μm ( C and F ).
D1r Agonist Skf38393 3 M, supplied by HFS LTD, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/d1r+selective+agonist+skf38393/d1r+agonist+skf38393+3+m/pm29107639-223-59-68
Average 90 stars, based on 1 article reviews
d1r agonist skf38393 3 m - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
d1 receptor agonist skf 38393  (Tocris)
99
Tocris d1 receptor agonist skf 38393
( A ) Experimental design. ( B ) Schematic of viral transfection. ( C ) Representative images of virus injection and fiber implant in CL. ( D ) Heatmap of DA3h fluorescence (left), quantification (middle), and AUC (right) of ΔF/F in CL. n = 5 mice/group. ( E ) The protein levels of <t>D1R</t> in CL. The protein levels of D1R following the METH CPP-Test. n = 3 mice/group. ( F ) Immunofluorescence of c-Fos + CaMKII + D1R + neurons in CL. Mean gray value of D1R CaMKII following METH CPP-Test. n = 6 mice/group. * P < 0.05. Two-tailed unpaired t test ( D – F ). Scale bars: 100 μm ( C and F ).
D1 Receptor Agonist Skf 38393, supplied by Tocris, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/d1r+selective+agonist+skf38393/Tocriscreen+2%2E0+Max/pmc07027730-66-6-13
Average 99 stars, based on 1 article reviews
d1 receptor agonist skf 38393 - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier

Image Search Results


a Dopamine concentration (in pg/μL) in infected Control (Ctrl, white) and Brainless (BR – , gray) embryos at early stage 35, measured by liquid chromatography–mass spectrometry (LC–MS/MS). Unpaired t -test * P < 0.05. b Survival rates (in percentage) of Ctrl (white) and BR – (gray) infected embryos after pharmacological treatment with drugs targeting the type-1 or type-2 family of dopamine (DA) receptors (D1R, D2R). Two-way ANOVA P < 0.01; P values after Bonferroni post hoc test are indicated as ** P < 0.01, ns P > 0.05. a , b Data represent the mean and S.D. of three independent replicates of 30 embryos. Each replicate is shown by one dot. See also Supplementary Fig. . c , d Drawings represent the morphological and molecular events occurs in response to infection, in presence ( c ) or absence ( d ) of brain. Unique neural- and immune-related pathways are indicated in blue. Upregulation and downregulation of transcripts are indicated in black. E. coli is represented by red circles; apoptotic cells are represented by cyan circles; mmp7 + cells (early macrophages) are represented by pink stars; dopamine-activated macrophages are represented with a D on the pink star. Complete list of genes is presented in Supplementary Data . Green = down gene, Red = up gene. All measured genes found in a pathway are located in Supplementary Data .

Journal: NPJ Regenerative Medicine

Article Title: An in vivo brain–bacteria interface: the developing brain as a key regulator of innate immunity

doi: 10.1038/s41536-020-0087-2

Figure Lengend Snippet: a Dopamine concentration (in pg/μL) in infected Control (Ctrl, white) and Brainless (BR – , gray) embryos at early stage 35, measured by liquid chromatography–mass spectrometry (LC–MS/MS). Unpaired t -test * P < 0.05. b Survival rates (in percentage) of Ctrl (white) and BR – (gray) infected embryos after pharmacological treatment with drugs targeting the type-1 or type-2 family of dopamine (DA) receptors (D1R, D2R). Two-way ANOVA P < 0.01; P values after Bonferroni post hoc test are indicated as ** P < 0.01, ns P > 0.05. a , b Data represent the mean and S.D. of three independent replicates of 30 embryos. Each replicate is shown by one dot. See also Supplementary Fig. . c , d Drawings represent the morphological and molecular events occurs in response to infection, in presence ( c ) or absence ( d ) of brain. Unique neural- and immune-related pathways are indicated in blue. Upregulation and downregulation of transcripts are indicated in black. E. coli is represented by red circles; apoptotic cells are represented by cyan circles; mmp7 + cells (early macrophages) are represented by pink stars; dopamine-activated macrophages are represented with a D on the pink star. Complete list of genes is presented in Supplementary Data . Green = down gene, Red = up gene. All measured genes found in a pathway are located in Supplementary Data .

Article Snippet: We used specific agonists and antagonists of each dopamine receptor: 10 μM SKF-38393, D1R agonist (SKF, Tocris 0922); 10 μM SCH-23390, D1R antagonist (SCH, Tocris 0925); 10 μM Quinpirole, D2R agonist (Quin, Tocris 1061); 1 μM L-741,626, D2R antagonist (L741, Tocris 1003).

Techniques: Concentration Assay, Infection, Control, Liquid Chromatography, Mass Spectrometry, Liquid Chromatography with Mass Spectroscopy

( A ) Experimental design. ( B ) Schematic of viral transfection. ( C ) Representative images of virus injection and fiber implant in CL. ( D ) Heatmap of DA3h fluorescence (left), quantification (middle), and AUC (right) of ΔF/F in CL. n = 5 mice/group. ( E ) The protein levels of D1R in CL. The protein levels of D1R following the METH CPP-Test. n = 3 mice/group. ( F ) Immunofluorescence of c-Fos + CaMKII + D1R + neurons in CL. Mean gray value of D1R CaMKII following METH CPP-Test. n = 6 mice/group. * P < 0.05. Two-tailed unpaired t test ( D – F ). Scale bars: 100 μm ( C and F ).

Journal: The Journal of Clinical Investigation

Article Title: A midbrain–cortical circuit mediated by a claustrum neuronal ensemble orchestrates drug-paired context memory processing

doi: 10.1172/JCI196944

Figure Lengend Snippet: ( A ) Experimental design. ( B ) Schematic of viral transfection. ( C ) Representative images of virus injection and fiber implant in CL. ( D ) Heatmap of DA3h fluorescence (left), quantification (middle), and AUC (right) of ΔF/F in CL. n = 5 mice/group. ( E ) The protein levels of D1R in CL. The protein levels of D1R following the METH CPP-Test. n = 3 mice/group. ( F ) Immunofluorescence of c-Fos + CaMKII + D1R + neurons in CL. Mean gray value of D1R CaMKII following METH CPP-Test. n = 6 mice/group. * P < 0.05. Two-tailed unpaired t test ( D – F ). Scale bars: 100 μm ( C and F ).

Article Snippet: The DA hydrochloride (ASL279, MedChemExpress) or D1R agonist (±)-SKF-38393 hydrochloride (SKF-38393, MedChemExpress) was diluted to 10 mM in 0.9% saline by shaking.

Techniques: Transfection, Virus, Injection, Fluorescence, Immunofluorescence, Two Tailed Test

( A ) Experimental design and timeline. ( B ) Schematic of viral transfection. ( C ) Representative images of virus injection and cannula implantation in VTA or CL. ( D ) Analysis of CPP behavior of time spent in CPP apparatus. S-CNO+Veh/S-CNO+DA group, n = 6 mice/group; M-CNO+Veh/M-CNO+DA group, n = 8 mice/group. ( E ) Representative heatmap of time spent in CPP apparatus during CPP-Test. ( F ) Experimental design and timeline. ( G ) Schematic of viral transfection. ( H ) Representative images of virus injection and cannula implantation in VTA or CL. ( I ) Analysis of CPP behavior of time spent in CPP apparatus. S-CNO+Veh/S-CNO+SKF group, n = 5 mice/group; M-CNO+Veh/M-CNO+SKF group, n = 6 mice/group. ( J ) Representative heatmap of time spent in CPP apparatus during CPP-Test. ( K ) Experimental design and timeline. ( L ) Schematic of viral transfection. ( M ) Representative images of virus injection in CL. ( N ) Analysis of CPP behavior and heatmap of time spent in CPP apparatus. S-CTRL/S-KD group, n = 6 mice/group; M-CTRL/M-KD group, n = 8 mice/group. ( O ) Representative heatmap of time spent in CPP apparatus during CPP-Test. ( P ) Immunofluorescence of c-Fos + D1R + EGFP + neurons in CL following CPP-Test. The percentage of c-Fos + EGFP + neurons in EGFP + neurons of CL. n = 6 mice/group. NS, P > 0.05, * P < 0.05, ** P < 0.01. Two-way ANOVA with Šidák’s multiple-comparison test ( D , I , N , and P ). Scale bars: 100 μm ( C , H , M , and P ).

Journal: The Journal of Clinical Investigation

Article Title: A midbrain–cortical circuit mediated by a claustrum neuronal ensemble orchestrates drug-paired context memory processing

doi: 10.1172/JCI196944

Figure Lengend Snippet: ( A ) Experimental design and timeline. ( B ) Schematic of viral transfection. ( C ) Representative images of virus injection and cannula implantation in VTA or CL. ( D ) Analysis of CPP behavior of time spent in CPP apparatus. S-CNO+Veh/S-CNO+DA group, n = 6 mice/group; M-CNO+Veh/M-CNO+DA group, n = 8 mice/group. ( E ) Representative heatmap of time spent in CPP apparatus during CPP-Test. ( F ) Experimental design and timeline. ( G ) Schematic of viral transfection. ( H ) Representative images of virus injection and cannula implantation in VTA or CL. ( I ) Analysis of CPP behavior of time spent in CPP apparatus. S-CNO+Veh/S-CNO+SKF group, n = 5 mice/group; M-CNO+Veh/M-CNO+SKF group, n = 6 mice/group. ( J ) Representative heatmap of time spent in CPP apparatus during CPP-Test. ( K ) Experimental design and timeline. ( L ) Schematic of viral transfection. ( M ) Representative images of virus injection in CL. ( N ) Analysis of CPP behavior and heatmap of time spent in CPP apparatus. S-CTRL/S-KD group, n = 6 mice/group; M-CTRL/M-KD group, n = 8 mice/group. ( O ) Representative heatmap of time spent in CPP apparatus during CPP-Test. ( P ) Immunofluorescence of c-Fos + D1R + EGFP + neurons in CL following CPP-Test. The percentage of c-Fos + EGFP + neurons in EGFP + neurons of CL. n = 6 mice/group. NS, P > 0.05, * P < 0.05, ** P < 0.01. Two-way ANOVA with Šidák’s multiple-comparison test ( D , I , N , and P ). Scale bars: 100 μm ( C , H , M , and P ).

Article Snippet: The DA hydrochloride (ASL279, MedChemExpress) or D1R agonist (±)-SKF-38393 hydrochloride (SKF-38393, MedChemExpress) was diluted to 10 mM in 0.9% saline by shaking.

Techniques: Transfection, Virus, Injection, Immunofluorescence, Comparison